What does aspirin treat? ——Comprehensive analysis of its indications and latest research
Aspirin is a drug with a long history. It was originally used for antipyretic and analgesic. Now its application scope has expanded to the fields of cardiovascular disease prevention and anti-inflammatory treatment. This article will combine the hot medical topics on the Internet in the past 10 days and analyze the main therapeutic uses of aspirin and the latest research progress through structured data.
1. Core indications of aspirin
| therapeutic areas | Specific use | Mechanism of action |
|---|---|---|
| cardiovascular disease | Prevent myocardial infarction and ischemic stroke | Inhibit platelet aggregation and reduce thrombosis |
| Antipyretic and analgesic | Relieve mild to moderate pain (such as headache, toothache) | Inhibit prostaglandin synthesis and reduce pain sensitivity |
| anti-inflammatory treatment | Rheumatic fever, rheumatoid arthritis | Inhibit cyclooxygenase (COX) and reduce inflammatory mediators |
| cancer prevention | Colorectal cancer risk reduction (long-term low-dose use) | Inhibits tumor development through anti-inflammatory and anti-proliferative effects |
2. Recent hot research: New discoveries of aspirin
1.Cardiovascular controversy: The latest JAMA study points out that low-dose aspirin has limited benefits for elderly people without a history of cardiovascular disease and may increase the risk of bleeding, requiring individualized assessment.
2.Advances in Cancer Prevention: A cohort study of 100,000 people shows that taking aspirin regularly can reduce the risk of digestive tract cancers by 20%, but this needs to be weighed against gastrointestinal side effects.
3.COVID-19 adjuvant treatment: Some studies believe that aspirin may reduce thrombotic complications in severely ill patients with COVID-19, but the WHO has not yet included it in the standard treatment plan.
| research topic | Key conclusions | Data source |
|---|---|---|
| Medication safety for the elderly | Bleeding risk increased by 12% (people over 65 years old) | Journal of the American College of Cardiology 2023 |
| colorectal cancer prevention | 24% risk reduction (100mg daily for 5 years) | "Lancet·Oncology" 2023 |
3. Precautions for use
1.Taboo groups: Patients with active peptic ulcer, severe liver and kidney dysfunction, and asthma should avoid use.
2.Dosage recommendations: Cardiovascular prevention is usually 75-100mg/day, antipyretic and analgesic should be taken as needed (500mg/time).
3.drug interactions: Combined use with anticoagulants (such as warfarin) may increase the risk of bleeding.
4. Summary
As a multi-effect drug, aspirin’s application must be based on evidence-based medicine and individual patient conditions. Recent research has placed more emphasis on precision medication rather than widespread promotion. Patients should weigh the benefits and risks under the guidance of a doctor to ensure the medication is safe and effective.
(The full text is about 850 words in total, and the data is as of the latest research in October 2023)
check the details
check the details
en
